产品货号：
Z32976
中文名称：
Alix/PDCD6IP抗体
英文名称：
Anti-Alix/PDCD6IP Antibody (Clone#14D10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Alix/PDCD6IP Antibody (Clone#14D10) |
| 指标别名 | AIP1;ALG 2 interacting protein 1;Alix;DRIP4;HP95;KIAA1375;PDCD6 interacting protein;PDCD6IP |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PDCD6IP |
| 克隆号 | 14D10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human PDCD6IP recombinant protein (Position:A2-D330).Human PDCD6IP shares 96.7% and 95.2% amino acid (aa) sequence identity with mouse and rat PDCD6IP,respectively. |
| 实际分子量 | 96KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Programmed cell death 6-interacting protein is a protein that in humans is encoded by the PDCD6IP gene.This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis,in intralumenal endosomal vesicle formation,and in enveloped virus budding.Studies using mouse cells have shown that overexpression of this protein can block apoptosis.In addition,the product of this gene binds to the product of the PDCD6 gene,a protein required for apoptosis,in a calcium-dependent manner.This gene product also binds to endophilins,proteins that regulate membrane shape during endocytosis.Overexpression of this gene product and endophilins results in cytoplasmic vacuolization,which may be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q8WUM4 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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